abstract：:Recent reports characterizing the physiological properties of normal human labial acini are reviewed with particular emphasis on mechanisms related to fluid secretion. In contrast to the salivary glands of several experimental animals, human labial acinar cells do not appear to have a1-adrenergic receptors, substance ...

journal_title：Archives of oral biology

authors： Turner RJ,Paulais M,Valdez II,Evans RL,Fox PC

更新日期：1999-05-01 00:00:00

abstract：:Cell shape in salivary glands is affected by mechanical forces. In the acini and ducts cell shape is modified by the contractions of the myoepithelial cells in both the secretory and ductal portions of the glands. At the organ level shape changes are due to muscle contraction during mastication, food intake and speech...

journal_title：Archives of oral biology

authors： Zelles T,Boros I,Varga G

更新日期：1999-05-01 00:00:00

abstract：:To test the hypothesis that human tooth eruption requires a critical time period during which no force is applied to the erupting tooth, the eruption of a maxillary second premolar in the prefunctional stage was recorded during the afternoon or evening hours in eight children, using an optical device based on the prin...

journal_title：Archives of oral biology

authors： Gierie WV,Paterson RL,Proffit WR

更新日期：1999-05-01 00:00:00

abstract：:Proteases produced by Porphyromonas gingivalis are believed to contribute to the pathogenesis of periodontal diseases. Here the cytotoxic effects of a purified preparation of a P. gingivalis protease with trypsin-like specificity were tested on human gingival fibroblasts in vitro. The active protease induced apoptotic...

journal_title：Archives of oral biology

authors： Wang PL,Shirasu S,Shinohara M,Daito M,Oido M,Kowashi Y,Ohura K

更新日期：1999-04-01 00:00:00

abstract：:Human salivary alpha-amylase participates in the initial digestion of starch and may be involved in the colonization of viridans streptococci in the mouth. To elucidate the role of histidine residues located near the starch-binding site on the streptococcal-binding activity, the wild type and three histidine mutants, ...

journal_title：Archives of oral biology

authors： Tseng CC,Miyamoto M,Ramalingam K,Hemavathy KC,Levine MJ,Ramasubbu N

更新日期：1999-02-01 00:00:00

abstract：:The ability of cadmium (Cd) to induce the synthesis of metallothionein (MT) in the developing teeth of the rat was investigated. Rats were given daily intraperitoneal injections of cadmium chloride (1.5 mg Cd/kg) for 7 days. The induction of MT synthesis in incisor teeth after Cd treatment was investigated immunohisto...

journal_title：Archives of oral biology

authors： Tamura Y,Wysocki GP,Cherian MG

更新日期：1999-01-01 00:00:00

abstract：:The periodontal ligament (PDL) contains precursor cells for osteoblasts and cementoblasts. It has been shown that epidermal growth factor (EGF) inhibits dexamethasone-induced differentiation and up-regulates EGF-receptor (EGF-R) expression, whereas EGF-R is down-regulated in the course of differentiation. Thus it was ...

journal_title：Archives of oral biology

authors： Matsuda N,Yokoyama K,Takeshita S,Watanabe M

更新日期：1998-12-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) and heparan sulphate (HS) were detected immunohistochemically in mandibular condylar cartilage, and the findings compared with those on epiphyseal articular cartilage. In the condylar cartilage, both bFGF and HS were localized in chondrocytes throughout the various zones including...

journal_title：Archives of oral biology

authors： Tajima Y,Kawasaki M,Kurihara K,Ueha T,Yokose S

更新日期：1998-11-01 00:00:00

abstract：:Serotonin (5-HT) stimulates tooth-germ development in embryonic mouse mandibular explant cultures, but it is not clear whether this is due to a direct action on epithelial-mesenchymal interactions, or whether development was stimulated indirectly by serotonergic regulation of other morphoregulatory molecules. A calciu...

journal_title：Archives of oral biology

authors： Moiseiwitsch JR,Raymond JR,Tamir H,Lauder JM

更新日期：1998-10-01 00:00:00

abstract：:The transforming growth factor (TGF)-beta superfamily comprises more than 35 structurally related genes that have been implicated in embryonic induction and morphogenesis. Different superfamily members may have distinct regulatory roles in tooth development and maintenance. Degenerate primer sets derived from the high...

journal_title：Archives of oral biology

authors： Nakashima M,Toyono T,Murakami T,Akamine A

更新日期：1998-09-01 00:00:00

abstract：:Twenty-five premolars (from Nagoya, Japan < 0.1 parts/10(-6)F in drinking water) were sampled to determine the fluoride content in imbrication lines of Retzius between the grooves and ridges of perikymata on the enamel surface. Eight small windows were formed on each surface in groove and ridge regions using an etched...

journal_title：Archives of oral biology

authors： Huang A,Nakagaki H,Tsuboi S,Ji H,Ohno N,Chen R,Nguyen TT,Kim JB

更新日期：1998-09-01 00:00:00

abstract：:In magnetic-stimulation studies where motor-evoked potentials (MEP) are measured on different occasions, accurate relocation of the stimulation site on the scalp is essential. Here a novel method of locating neural stimulation sites was tested and the reproducibility of MEPs in the human masseter assessed. The heads o...

journal_title：Archives of oral biology

authors： McMillan AS,Watson C,Walshaw D,Taylor JP

更新日期：1998-08-01 00:00:00

abstract：:The purpose of this study was firstly to characterize the changes occurring in size and form of the mineralizing maxillary second primary molar and first permanent molar crowns, and secondly to determine if similar changes in size and form characterize enamel apposition in the crowns of these teeth. Twenty-five primar...

journal_title：Archives of oral biology

authors： Peretz B,Nevis N,Smith P

更新日期：1998-07-01 00:00:00

abstract：:Culture of the developing dental tissues has contributed to understanding of developmental processes during early odontogenesis. However, to understand fully the mechanisms involved during dentinogenesis and tissue repair there is a need to develop culture models for the dentine-pulp complex from more mature dental ti...

journal_title：Archives of oral biology

authors： Sloan AJ,Shelton RM,Hann AC,Moxham BJ,Smith AJ

更新日期：1998-06-01 00:00:00

abstract：:Tartrate-resistant acid phosphatase (TRAPase)-positive cells were examined during the early morphogenesis of mouse mandibular first molar teeth, using a simultaneous azo dye-coupling technique and confocal laser scanning microscopy (CLSM). CLSM of paraffin-embedded sections revealed that cells exhibiting TRAPase fluor...

journal_title：Archives of oral biology

authors： Sakakura Y,Yajima T,Tsuruga E

更新日期：1998-05-01 00:00:00

abstract：:The biological activity of carboxyl-terminal parathyroid hormone peptide[53-84] (PTH[53-84]) and aminoterminal peptide [1-34] (PTH[1-34]) during cultivation of the lower molar tooth germ from mouse embryos was examined. PTH[1-34] increased alkaline phosphatase activity in the tooth germ at an early developmental stage...

journal_title：Archives of oral biology

authors： Tsuboi T,Togari A

更新日期：1998-04-01 00:00:00

abstract：:Prostaglandins are involved in force-induced orthodontic tooth movement. Bradykinin (BK) and thrombin are known to cause a significant time- and concentration-dependent burst of prostanoid biosynthesis in cultured human periodontal-ligament (PDL) cells. The aim now was to investigate interactive effects between interl...

journal_title：Archives of oral biology

authors： Ransjö M,Marklund M,Persson M,Lerner UH

更新日期：1998-04-01 00:00:00

abstract：:The effect of this axotomy on the expression of vasoactive intestinal polypeptide (VIP) in trigeminal ganglion neurones and nerve fibres in the first molar was examined immunohistochemically 3 weeks postsurgically in rats. A distinct upregulation of VIP-like immunoreactivity was found in 3 to 4% of the neurones (mean ...

journal_title：Archives of oral biology

authors： Fristad I,Jacobsen EB,Kvinnsland IH

更新日期：1998-03-01 00:00:00

abstract：:In culture, chondrocytes of Meckel's cartilage can differentiate further to become bone-type collagen-synthesizing cells. Here, the replacement of type II collagen by type I collagen, accompanying expression of the osteocytic phenotype, was analysed by double immunofluorescence staining, histochemistry and electron mi...

journal_title：Archives of oral biology

authors： Ishizeki K,Kubo M,Yamamoto H,Nawa T

更新日期：1998-02-01 00:00:00

abstract：:Small, quasi-rhythmical tremor of the jaw occurs at rest and during voluntary movements. In peripheral limbs, tremor consists of a component due to mechanical resonance properties of the system, and a neurogenic component mediated by a central pacemaker or neural loops. The present study attempted to determine if thes...

journal_title：Archives of oral biology

authors： Junge D,Rosenberg JR,Halliday DM

更新日期：1998-01-01 00:00:00

abstract：:Human whole saliva was collected at 4 degrees C into a protein inhibitor cocktail to prevent proteolytic degradation. Saliva was clarified by centrifugation and fractionated by immobilized metal affinity chromatography (IMAC) after charging the column with zinc ions. Proteins with an affinity for zinc were eluted from...

journal_title：Archives of oral biology

authors： Davey HP,Embery G,Creeth JE,Cummins D

更新日期：1997-12-01 00:00:00

abstract：:Mechanisms of primary fluid formation by macropodine mandibular glands were investigated in anaesthetized red kangaroos using ion-transport and carbonic anhydrase inhibitors. Bumetanide at carotid plasma concentrations of 0.005-0.1 mmol/l progressively reduced a stable, acetylcholine-evoked flow rate of 1.02 +/- 0.024...

journal_title：Archives of oral biology

authors： Beal AM

更新日期：1997-10-01 00:00:00

abstract：:The aim was to examine the nature of enamel dissolution in aqueous suspensions with a high solid/solution ratio and in a CO2-rich atmosphere. Before experimentation, a water-saturated mixture of 95% N2-5% CO2 was passed through the acid solutions for 24 hr. Samples of 2 g of powdered enamel were suspended in 7 ml of e...

journal_title：Archives of oral biology

authors： Larsen MJ,Pearce EI,Ravnholt G

更新日期：1997-09-01 00:00:00

abstract：:Eight adult, Finnish 47,XYY males were compared with population male and female controls and, in addition, three of them were compared with first-degree male relatives. Linear and angular measurements were made from standardized lateral cephalograms of patients and normal population controls from the "Kvantti" study s...

journal_title：Archives of oral biology

authors： Grön M,Pietilä K,Alvesalo L

更新日期：1997-08-01 00:00:00

abstract：:To study the effects of increased occlusal vertical dimension on these kinetics, the actin-filament sliding velocity on masseter myosins in an in vitro motility assay and the ATPase activity of masseter myosins from normal (control) and bite-opened (5.6 mm increase in the vertical dimension for 1 week) guinea-pigs wer...

journal_title：Archives of oral biology

authors： Kawasaki K,Saeki Y,Ohnuki Y

更新日期：1997-07-01 00:00:00

abstract：:The Trk family, a group of high-affinity neurotrophin receptors, is divided into three subtypes, TrkA, TrkB and TrkC. These were originally found in neural elements, and are involved in neural development, maintenance and survival. Recent studies have shown that non-neural cells in vitro also express mRNA encoding som...

journal_title：Archives of oral biology

authors： Ochi K,Saito I,Hanada K,Maeda T

更新日期：1997-06-01 00:00:00

abstract：:The eruption of the deciduous teeth in Down's individuals is reportedly delayed, but the extent of delay in comparison to normal children has been little studied. The eruption characteristics of the deciduous teeth in a sample of Chilean individuals with Down's syndrome were compared with those of the normal Chilean p...

journal_title：Archives of oral biology

authors： Ondarza A,Jara L,Muñoz P,Blanco R

更新日期：1997-05-01 00:00:00

abstract：:The localization of cathepsin L and rat salivary cystatin-3 (RSC-3) in rat osteoclasts (rat femoral and alveolar bones) treated with or without E-64 (control) was examined immunocytochemically. In osteoclasts pretreated with E-64, immunoreactivity for cathepsin L was very weak extracellularly compared to that in the c...

journal_title：Archives of oral biology

authors： Moroi R,Yamaza T,Nishiura T,Nishimura Y,Terada Y,Abe K,Himeno M,Tanaka T

更新日期：1997-04-01 00:00:00

abstract：:To investigate whether mechanical deformation of osteoblasts exerts an influence upon parathyroid hormone (PTH)-induced bone resorption, the effect of medium conditioned by a statistically stretched, osteoblast-enriched, bone cell population on PTH-induced osteoclast-like cell formation in mouse bone marrow cultures w...

journal_title：Archives of oral biology

authors： Soma S,Matsumoto S,Takano-Yamamoto T

更新日期：1997-03-01 00:00:00

abstract：:The enzymatic degradation of sodium monofluorophosphate by whole saliva in patients with differing oral health status was compared Ten patients each with good or poor oral health were selected. Assessment of oral health status included indices of the amount of dental plaque, caries experience and counts of Streptococc...

journal_title：Archives of oral biology

authors： Klimek J,Jung M,Jung S

更新日期：1997-02-01 00:00:00

abstract：:The fragmentation of foods (breakage function) was measured in five humans on "bagged' single particles of 28 foods from three food groups. The change in the square root of the specific surface of the particles (the specific surface being the area of particle silhouettes, measured by image analysis, divided by origina...

journal_title：Archives of oral biology

authors： Agrawal KR,Lucas PW,Prinz JF,Bruce IC

更新日期：1997-01-01 00:00:00

abstract：:Counts of cultivable Porphyromonas gingivalis, assays of microbial proteases and the concentration in gingival crevicular fluid of proteoglycan metabolites were investigated at periodontitis and gingivitis sites in 16 patients with chronic adult periodontitis before and after treatment. Two periodontitis sites and two...

journal_title：Archives of oral biology

authors： Smith AJ,Wade W,Addy M,Embery G

更新日期：1997-01-01 00:00:00

abstract：:Tissue remodelling is an important feature during embryogenesis. Although the matrix metalloproteinases are believed to participate in these processes, the relation between matrix metalloproteinases and tissue remodelling during craniofacial morphogenesis remains unclear. The purpose of the study was to look for the p...

journal_title：Archives of oral biology

authors： Iamaroon A,Wallon UM,Overall CM,Diewert VM

更新日期：1996-12-01 00:00:00

abstract：:Most authorities agree that the hydrodynamic theory of dentine sensitivity best explains the stimulus-response relations of most painful stimuli. However, as the usual hydrodynamic stimuli are so different, it has been impossible to compare them. The equivalency of hydrodynamic stimuli can be evaluated from measuremen...

journal_title：Archives of oral biology

authors： Pashley DH,Matthews WG,Zhang Y,Johnson M

更新日期：1996-11-01 00:00:00

abstract：:This study sought to localize immunohistochemically Janus kinase (Jak) and Tyk isoforms and STAT-1 in association with events involved in early dentine and enamel formation in the rat molar. The Jaks and STATs (signal transducers and activators of transcription) are key signal-transduction pathway components in the cy...

journal_title：Archives of oral biology

authors： Tanase S,Bawden JW

更新日期：1996-10-01 00:00:00

abstract：:Samples of gingival crevicular fluid (GCF) were collected in 30 volunteers with inflamed gingiva, using either capillary tubes (cGCF) or Durapore strips (sGCF). They were examined, together with samples of serum from the same patients, by sodium dodecyl sulphate-polyacrylamide gel electrophoresis and/or by two-dimensi...

journal_title：Archives of oral biology

authors： Estreicher A,Broggiato A,Duroux P,Andersen E,Cimasoni G

更新日期：1996-08-01 00:00:00

abstract：:Adhesion molecules are considered to have an active role in controlling cell differentiation, although the mechanisms involved have yet to be determined. The developing tooth provides an excellent model to use for determining the factors/processes regulating cell differentiation. The studies presented here focused spe...

journal_title：Archives of oral biology

authors： MacNeil RL,Berry J,Strayhorn C,Somerman MJ

更新日期：1996-08-01 00:00:00

abstract：:Salivary gland intralobular ducts are responsible for the modification of the electrolyte composition of the primary fluid secreted by the acini. However, the intracellular messengers that regulate this and other intralobular duct cell processes have not been fully characterized. To investigate the possibility that cA...

journal_title：Archives of oral biology

authors： Evans RL,Perrott MN,Lau KR,Case RM

更新日期：1996-07-01 00:00:00

abstract：:Although mechanisms underlying chronic muscle pain are poorly understood, one prevalent theory is that it is due, in part, to localized hypoxia. The purpose of this study was to evaluate this theory using non-invasive near-infra-red spectroscopy that monitors relative changes in intramuscular haemoglobin (Hb) concentr...

journal_title：Archives of oral biology

authors： Delcanho RE,Kim YJ,Clark GT

更新日期：1996-06-01 00:00:00

abstract：:Mesiodistal dimensions of teeth in 59 relatives of 26 patients with oligodontia were evaluated and compared with the size of teeth of a control group (n = 66). It was found that the teeth of relatives do show reductions in size even in relatives with a full permanent dentition. In male relatives with a full permanent ...

journal_title：Archives of oral biology

authors： Schalk-van der Weide Y,Bosman F

更新日期：1996-05-01 00:00:00